The effect of plant lectins on the survival and malignant ...

2018-4-16 · In this present study, it has been aimed to determine the alteration of sialic acid and fucose expressions in the cell surface of human thyroid carcinoma cells and investigate the changes in tumorigenic and malignant characters after treating them with specific plant lectins. Our study showed that the cell surface glycan chains of anaplastic ...

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SUP-T1 [VB] | ATCC

The cells express multiple T lineage markers.The cells are E - rosette negative and beta 2 microglobulin positive.The cells are negative for Leu 5 (CD2), sheep erythrocyte receptor, OKT 9 (CD71; transferrin receptor), surface immunoglobulin (sIg -), HLA DR, CALLA (CD10) and Tac (CD25).

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Cytotocic effect of plant polyphenols and fat-soluble ...

1992-3-15 · Cancer Letters, 62 (1992) 217-224 Elsevier Scientific Publishers Ireland Ltd. 217 Cytotoxic effect of plant polyphenols and fat-soluble vitamins on malignant human cultured cells R. Ramanathan, C.H. Tan and N.P. Das Laboratory of Flavonoid Research, Department of Biochemistry, Faculty of Medicine, National University of Singapore, Kent Ridge Crescent, Singapore 0511 (Singapore) …

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On the Origin of Cancer Metastasis

These cells were commonly referred to as either "birds-eye" or "signet-ring" cells. 90,91 While this phagocytic/cannibalistic phenomenon is commonly seen in feeding microorganisms, cell cannibalism is also seen in malignant human tumor cells. 90-93 Fais and colleagues provided dramatic evidence of tumor cell phagocytosis in showing how ...

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Cancer Cell | Journal | ScienceDirect by Elsevier

Cancer Cell provides a high-profile forum to promote major advances in cancer research and oncology.The primary criterion for considering manuscripts is whether the studies provide major advances into answering important questions relevant to naturally occurring cancers.

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A Study on the Effect of Some Plant Extracts on Certain ...

2009-3-11 · A Study on the Effect of Some Plant Extracts on Certain Malignant Cell Lines in Vitro Prepared by Saib H. Al Owini Supervisors Dr. Abboud EL Kichaoui Dr. Basim Ayesh Submitted in Partial Fulfillment of the Requirements for the degree of Master of Biological Sciences/Zoology

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use of some plant extracts as an alternative approaches ...

activities of each cell line in response to each plant extract line in response to each plant extracts treatment and the determination of any morphological changes of each cell line in each time performing viability testing assay in parallel. 2. Methodology 2.1 Plant collection

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Plant lectins in cancer therapeutics: Targeting apoptosis ...

Plant lectins have found applications as cancer biomarkers for recognizing the malignant tumor cells for the diagnosis and prognosis of cancer. Interestingly, plant lectins contribute to inducing cell death through autophagy and apoptosis, indicating their potential implication in cancer inhibitory mechanism.

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Medicinal Plants: Their Use in Anticancer Treatment

2015-10-1 · b. Flavonoids. Flavonoids are from the polyphenolic compounds and constitute a large family of plant secondary metabolites with 10,000 known structures 19.They are physiologically active agents in plants and becoming of high interest scientifically for their health benefits 20-21.. Various plants have been investigated for their flavonoid content and how these compounds affect cancer cells ...

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Cancer | Whitehead Institute

2021-8-25 · Cancer. Image. Cancer hijacks a cell''s normal processes for its own ends, sidestepping the body''s immune system, and, too often, evading even the most promising treatments. But our researchers, who helped to define the field of cancer research, are driving a new foundation of knowledge for innovative diagnostics and therapeutics for ...

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Seneca | Home of Mobile Crushing & Screening

Seneca Crushing & Screening, a mobile crushing and screening contracting company, managed by a young, dynamic team, offers 15 years of experience in the fields of stone crushing and screening, quarrying and mining, and materials supply and handling for …

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Cytotoxic and Apoptotic Potential of Rheum turkestanicum ...

Malignant and non-malignant cells were cultured in RPMI 1640 medium and incubated with different concentrations of plant extracts. Cell viability was measured by MTS assay. Apoptotic cells were evaluated using PI staining of DNA fragmentation by flow cytometry (sub-G1 peak).

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Anticancer activities of Zanthoxylum bungeanum seed oil on ...

ZBSO possessed anticancer activities that were selectively effective to A375 cells. This study support the hypothesis that ZBSO is a capable candidate for anti-melanoma agent, and provide new insights for future work on investigating the utilization of ZBSO in malignant melanoma treatment.

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Introduction to DNA Cell Cycle Analysis

2008-9-12 · DNA aneuploid cell populations are almost always, but not exclusively, associated with malignant tissues. Exceptions that must be noted are some benign tumors (e.g. endocrine adenomas) and some premalignant epithelial cells (e.g. dysplastic epithelium in ulcerative colitis or colon adenomas).

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NK-92® MI | ATCC

NK-92® and this derivative cell line NK-92® MI have the following characteristics: surface marker positive for CD2, CD7, CD11a, CD28, CD45, CD54 and CD56 bright; surface marker negative for CD1, CD3, CD4, CD5, CD8, CD10, CD14, CD16, CD19, CD20, CD23, CD34 and HLA-DR. The parental IL-2 dependent cell line is available as ATCC CRL-2407 (NK-92® ). NK-92® MI was shown to contain, …

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Anti-cancer studies of noble metal nanoparticles ...

2011-5-10 · Biofunctionalized gold and silver nanoparticles synthesized using different plant extracts of guava and clove in vitro anti-cancer efficacy against four different cancer cell lines human colorectal adenocarcinoma, human kidney, human chronic myelogenous, leukemia, bone marrow, and human cervix have been studied and reported. The present experimental study suggests that flavonoids ...

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Dietary flavonoids and modulation of natural killer cells ...

Dietary flavonoids and modulation of natural killer cells: implications in malignant and viral diseases. Burkard M(1), Leischner C(2), Lauer UM(3), Busch C(4), Venturelli S(5), Frank J(6). Author information: (1)Institute of Physiology, Department of Physiology I, Medical University Hospital, Tuebingen, Germany. Electronic address: markus ...

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Construction, Working and Maintenance of Crushers for ...

2018-12-26 · 6 Construction, Working and Maintenance of Crushers for Crushing Bulk Materials shown in above figure, a closed circuit crushing system is a means of controlling product top size by screening the product and then returning oversize material to the feed end of …

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An in vitro inhibition of human malignant cell growth of ...

2014-12-3 · In vitro inhibition of human malignant cell growth Yusuf, U.F., et al. enzyme linamarase (EC 3.2.1.21), a β-glucosidase also tapped from the cassava plant and treated appropriately was tested on one of the cell lines. Crude water extract or commercial linamarin was added in a final con-

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Crushing Artifacts Resulting in Small Blue Cellular ...

2011-6-1 · Crushing Artifacts Resulting in Small Blue Cellular Clusters That Simulate Small Cell Carcinoma Federica Flamminio, MD, Anna Lisa Tosi, MD, and Giovanni Fellegara, MD International Journal of Surgical Pathology 2011 19 : 4, 487-491

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Long non-coding RNA UCA1 promotes malignant …

2020-1-29 · Accumulating literatures have indicated that long non-coding RNAs (lncRNAs) are potential biomarkers that play key roles in tumor development and progression. Urothelial cancer associated 1 (UCA1) is a novel lncRNA that acts as a potential biomarker and is involved in the development of cancers. However, the molecular mechanism of UCA1 in renal cancer is still needed to further explore.

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Deoxypodophyllotoxin isolated from Juniperus communis ...

Using bioassay-guided fractionation of a crude plant extract, we identified the diterpene isocupressic acid and the aryltetralin lignan deoxypodophyllotoxin (DPT) as potent inducers of caspase-dependent programmed cell death (apoptosis) in malignant MB231 breast cancer cells. Further elucidation revealed that DPT, in contrast to isocupressic ...

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In vitro effects of Sutherlandia frutescens water extracts ...

2009-7-6 · The in vitro effects of S. frutescens extracts were evaluated on cell numbers, morphology, cell cycle progression and cell death. Dose-dependent studies (2-10 mg/ml) revealed a decrease in malignant cell numbers when compared to their controls.

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In vitro anticancer activity of Spondias pinnata bark on ...

2013-5-18 · Cell proliferation assay. The effect of SPME on cell viability was evaluated individually by WST-1 assay and the IC 50 values were calculated from dose-dependent response studies assessed 48 h post-treatment. SPME inhibited the growth of both A549 and MCF-7 cells in a dose-dependent manner with an IC 50 value of 147.84 ± 3.74 and 149.34 ± 13.30 μg/ml, respectively.

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strength of plants: theory and experimental methods to ...

Introduction. A recent special issue on ''Plant Biomechanics and Mechanobiology'' in the Journal of Experimental Botany (2013, 64, 4617–4827) conveyed that there is increasing interest amongst biologists to examine the effects of mechanical forces on biological systems, including those from the phylum Plantae living plants, the multiscale interplay of growth, morphology, and external (i ...

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Effects of Monascus-fermented rice extract on malignant ...

Effects of Monascus-fermented rice extract on malignant cell-associated neovascularization and intravasation determined using the chicken embryo chorioallantoic membrane model Integr Cancer Ther . 2010 Jun;9(2):204-12. doi: 10.1177/1534735410365079.

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Phytoestrogens regulate the proliferation and expression ...

1. Int J Oncol. 2013 Nov;43(5):1385-94. doi: 10.3892/ijo.2013.2060. Epub 2013 Aug 20. Phytoestrogens regulate the proliferation and expression of stem cell factors in cell lines of malignant testicular germ cell …

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Crucial role of the pentose phosphate pathway in malignant ...

Interest in cancer metabolism has increased in recent years. The pentose phosphate pathway (PPP) is a major glucose catabolism pathway that directs glucose flux to its oxidative branch and leads to the production of a reduced form of nicotinamide adenine dinucleotide phosphate and nucleic acid. The PPP serves a vital role in regulating cancer cell …

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Pediatric malignant germ cell tumors: A comparison of the ...

Malignant germ cell tumors (GCT) arise from abnormal migration of primordial germ cells and are histologically identical whether they occur inside or outside the central nervous system (CNS). However, the treatment strategy for GCTs varies greatly depending on the location of the tumor.

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Cell Press: Cell Stem Cell

Cell Stem Cell publishes peer-reviewed articles describing novel results of unusual significance in all areas of stem cell research.

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RWPE-1 | ATCC

In 3-dimensional Matrigel culture, RWPE-1 cells organize into acini and secrete PSA into the lumen when exposed to androgen. RefBello-DeOcampo D, et al. Laminin-1 and alpha6beta1 integrin regulate acinar morphogenesis of normal and malignant human prostate epithelial cells. Prostate 46: 142-153, 2001. PubMed: 11170142 When injected with Matrigel or with stromal cells, into male athymic rodents ...

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